A project of the U.S. Department of Health and Human Services Office on Women's Health

Skip Navigation

Womens Health logo
divider line


Histoplasmosis (hiss-toh-plaz-MOH-suhss) is a disease caused by a fungus. The disease mainly hurts your lungs. Sometimes, it hurts other organs too, in which case your HIV has progressed to AIDS. Histoplasmosis can be fatal if untreated. The fungus grows in soil and in materials that are contaminated with bat or bird droppings (feces). The fungus gets into the air when soil (that has the fungus) is disturbed. Breathing it in causes infection. However, one person infected with histoplasmosis can't "give" it to someone else. Many people don't have symptoms. If they do, symptoms include fever, chest pains, fatigue, weight loss, breathing problems, swollen lymph nodes, pneumonia-like symptoms, and a dry (nonproductive) cough.

Anyone working at a job or close to places where the fungus is in the air can get this disease. But people with HIV, especially those with lower CD4 cell counts, have a higher risk of getting mild or severe disease. People with HIV should not do activities that raise their risk, like cleaning chicken coops, disturbing soil beneath bird-roosting sites, and exploring caves. Below are some jobs and hobbies that increase your risk:

  • Bridge inspector or painter
  • Chimney cleaner
  • Construction worker
  • Demolition worker
  • Farmer
  • Gardener
  • Heating and air-conditioning system installer or service person
  • Microbiology laboratory worker
  • Pest control worker
  • Restorer of historic or abandoned buildings
  • Roofer
  • Spelunker (cave explorer)

These activities involve being in sites that are likely not cleaned or tested for histoplasmosis. Talk to your doctor about how to protect yourself if you have to be near such a site. Your doctor may prescribe antifungal medications to treat a histoplasmosis infection.

Return to top

More information on Histoplasmosis

Explore other publications and websites

  • Facts About Histoplasmosis - This site discusses histoplasmosis and risk of eye disease caused by this infection. It also includes treatment information for people who experience eye problems as the result of histoplasmosis.
  • Histoplasmosis - This publication answers frequently asked questions about the causes, symptoms, and treatments for histoplasmosis.
  • Histoplasmosis - This publication has information about histoplasmosis causes, symptoms, tests, treatment, and possible complications.

Content last updated: July 01, 2011.

Return to top